Cases Journal


Open Access Case Report

Interstitial lung disease associated to erlotinib treatment: a case report

Yolanda del Castillo*, Paulina Espinosa, Fernanda Bodí, Raquel Alcega, Emma Muñoz, Carlos Rabassó and David Castander

Author Affiliations

Unidad de Cuidados Intensivos, Hospital de Sant Pau i Santa Tecla, Rambla Vella, 14. 43003, Tarragona, Spain

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Cases Journal 2010, 3:59 doi:10.1186/1757-1626-3-59

Published: 12 February 2010

Abstract

Introduction

Few cases of pulmonary toxicity related to epidermal growth factor receptor-targeted agents have been described.

Case presentation

We report a case of a 63-year-old white male with stage IV non-small cell lung cancer treated with erlotinib who developed a interstitial lung disease.

Conclusion

Respiratory symptoms during treatment with erlotinib should alert clinicians to rule out pulmonary toxicity. Early erlotinib withdrawal and corticoid administration were successful.