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Successful treatment of tracheal stenosis by rigid bronchoscopy and topical mitomycin C: a case report

Jyi L Wong1*, Siew T Tie1, Bohari Samril2, Chee L Lum2, Mohammad RA Rahman3 and Jamalul AA Rahman1

Author Affiliations

1 Department of Respiratory Medicine, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Malaysia

2 Department of Othorhinolaryngology, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Malaysia

3 Department of Anaesthesiology, Queen Elizabeth Hospital, Kota Kinabalu, Sabah, Malaysia

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Cases Journal 2010, 3:2 doi:10.1186/1757-1626-3-2

Published: 4 January 2010

Abstract

Tracheal stenosis is a known complication of prolonged intubation. It is difficult to treat and traditional surgical approach is associated with significant risk and complications. Recurrent stenosis due to granulation tissue necessitates repeated procedures. We describe a case of short web-like tracheal stenosis (concentric membranous stenosis less than 1 cm in length without associated cartilage damage) managed by a minimally invasive thoracic endoscopic approach. Topical application of Mitomycin C, a potent fibroblast inhibitor reduces granulation tissue formation and prevents recurrence.