Case Report

Plasma cells increased markedly in lymph node in hemophagocytic syndrome: a case report

Li Congyang¹ , Hu Xuexin¹ , Li Hao² , Li Chunge³ and Miao Yingye²

¹  Department of Pathology, People's Liberation Army 152 hospital, Pingdingshan City, Henan province, PR China

²  Department of Clinical Laboratories, People's Liberation Army 152 hospital, Pingdingshan City, Henan province, PR China

³  Department of Pathology, Pingdingshan First People's Hospital, Pingdingshan City, Henan province, PR China

author email corresponding author email

Cases Journal 2009, 2:9096doi:10.1186/1757-1626-2-9096

Published:	27 November 2009

Abstract

Introduction

Hemophagocytic syndrome is a rare clinicopathological condition characterized by the activation of the mononuclear phagocyte system, resulting in hemophagocytosis in the reticuloendothelial systems. The pathogenesis of HPS remains unclear.

Case presentation

We report the case of a 20-year-old soldier suffering from HPS. Because of long history fever and no reasons being found, his left groin lymph node and left neck lymph node biopsy were done with two weeks interval. We found a marked increase in plasma cells in left neck lymph node during the course of the disease.

Conclusion

Our result provides a new thought for the researchers to understand the mechanisms responsible for the phagocytosis in HPS.