Cases Journal


Open Access Case Report

A 70-year-old male having advanced prostate cancer presenting with hypercalcemia and diffuse osteoblastic bone metastases: a case report

Wan-Hsiu Liao1, Sheng-Hsiang Lin2* and Tsu-Tuan Wu2

Author Affiliations

1 Department of Family Medicine, Taipei County Hospital, Taipei county, Taiwan (ROC)

2 Department of Internal Medicine, Taipei County Hospital, Taipei county, Taiwan (ROC)

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Cases Journal 2009, 2:54 doi:10.1186/1757-1626-2-54

Published: 14 January 2009

Abstract

Background

Bony metastases were occasionally the initial presentations of malignancy. Overlooking of bony changes on radiographs in cancer patients with non-specific clinical symptoms may lead to delayed diagnosis.

Case presentation

We presented a 70-year-old male having hypercalcemia and diffuse osteoblastic bone metastases on routine plain films. Finally, prostate cancer was diagnosed with a prostate needle biopsy.

Conclusion

Although the modern radionuclide bone scanning is useful in diagnosis, osteoblastic bone changes are occasionally seen in plain films, which are frequently overlooked. To avoid delayed diagnosis, bony structures should be carefully examined in all plain-film radiographs.