Cases Journal


Open Access Case Report

Malignant melanoma associated with a blue naevus: a case report

Pasquale Mellone1, Alexander Bianchi1, Emanuele Dragonetti2, Raffaele Murace3, Paolo Persichetti4 and Alfonso Baldi1*

Author Affiliations

1 Department of Biochemistry, Sect. Pathology, Second University of Naples, Naples, Italy

2 Rome American Hospital, Rome, Italy

3 Paideia Hospital, Rome, Italy

4 Campus BioMedico University, Rome, Italy

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Cases Journal 2008, 1:433 doi:10.1186/1757-1626-1-433

Published: 31 December 2008

Abstract

Introduction

Combined malignant naevi are characterised pathologically by the association of a melanoma with one or more different types of benign melanocytic naevi in a single lesion.

Case Presentation

We show here a case of malignant combined naevus made up of a blue naevus and a melanoma, presenting as a slowly progressing and asymptomatic pigmented lesion on the trunk of a 35-year-old man. Dermoscopic examination was not conclusive for a malignant lesion, showing only an atypical brown pigment network. The definitive diagnosis was reached only at the hystopathological examination.

Conclusion

This finding suggests that combined naevi should be always excised and histologically examined to achieve a correct diagnosis and avoid risk of misclassification.