Cases Journal


Open Access Case Report

Chronic fungal sinusitis leading to disastrous cerebral aspergillosis: a case report

Muhammad J Popalzai*, Anurag Kushawaha, Neville Mobarakai, Rohail Asrar and Farida Durrani

Author Affiliations

Department of Medicine, Staten Island University Hospital, Division of Infectious Diseases 475 Seaview Avenue, Staten Island, NY 10305, USA

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Cases Journal 2009, 2:9406 doi:10.1186/1757-1626-2-9406

Published: 31 December 2009

Abstract

Cerebral angioinvasion is a fatal complication of disseminated aspergillosis and has been rarely described in diabetic population in the absence of ketoacidosis. We present a case of invasive fungal sinusitis in a 79 year old diabetic man who presented with chronic frontal headaches. Despite appropriate medical and surgical treatment, the disease progressed and the patient eventually succumbed to a fatal ruptured mycotic aneurysm. We emphasize that clinicians should consider this in the differential diagnoses of all diabetics who present with chronic sinusitis, as early diagnosis could be the key in the successful treatment.