Cases Journal


Open Access Case Report

Mucosa associated lymphoid tissue lymphoma of the colon: a case report

Cem Gezen1, Metin Kement1*, Mustafa Oncel1, Erhan Tuncay1, Taflan Sahlepci2 and Serdar Alkan1

Author Affiliations

1 Department of Surgery, Kartal Education and Research Hospital, Istanbul, Turkey

2 Department of Oncology, Kartal Education and Research Hospital Istanbul, Turkey

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Cases Journal 2009, 2:9316 doi:10.1186/1757-1626-2-9316

Published: 14 December 2009

Abstract

A 65-year-old man had suffered from rectal bleeding during defecation for a few weeks, admitted to our department. Laboratory findings were normal except a slight elevation in the level of alkaline phosphatase. Multiple polypoid lesions were observed in colonoscopic examination. The histological and immunochemical evaluation showed atypical lymphoid cell proliferation and lymphoepithelial lesions on the colonic mucosa, staining with CD20 (CD20 × 100). After the diagnosis had been confirmed as low grade mucosa associated lymphoid tissue lymphoma. Abdominal computed tomography revealed polypoid lesions throughout the colon and multiple milimetrics lymphadenopathies in the mesentery. The patient was treated with a chemotherapy regimen. During the follow-up, colonoscopic examination and blind biopsies were repeated in every 6 months, revealed endoscopically and pathologically normal mucosa each time. The patient is still alive without any recurrence of the disease 36 months after the diagnosis.