Cases Journal


Open Access Case Report

Incredibly late thromboses in first generation drug eluting stents: a case series

Zakir Shaik1*, Khaja S Mohammed2, Adnan Siddiqi2, Ilyas Mohammed1, Timothy A Shapiro2 and Thomas P Phiambolis2

Author Affiliations

1 Department of Internal Medicine, Main Line Health, Lankenau Hospital, 100 Lancaster Road, Wynnewood, Pennsylvania 19096, USA

2 Division of Cardiology, Main Line Health, Lankenau Hospital, 100 Lancaster Road, Wynnewood, Pennsylvania 19096, USA

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Cases Journal 2009, 2:9303 doi:10.1186/1757-1626-2-9303

Published: 10 December 2009

Abstract

Background

The drug-eluting stents have decreased the incidence of instent restenosis compared to bare metal stents. But, the incidence of late and very late stent thrombosis has increased with the drug-eluting stents.

Case presentation

We are here, reporting three cases of incredibly late instent thrombosis, each one occurring after more than 50 months of drug-eluting stent placement.

Conclusion

The occurrence of stent thrombosis as late as 5 years has been reported in literature. This highlights the importance that there may be no limit to the time duration to the occurrence of very late stent thrombosis and dual antiplatelet therapy with aspirin and clopidogrel may have to be continued indefinitely in patients with drug-eluting stents.