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Open Access Open Badges Case Report

Sepsis requiring intensive care following intramuscular injections: two case reports

Dimitrios Velissaris1, Charis Matzaroglou2, Christina Kalogeropoulou3, Vassilios Karamouzos1, Kriton Filos1 and Menelaos Karanikolas1*

Author Affiliations

1 Department of Anaesthesiology and Critical Care Medicine, Patras University Hospital, Rion 26500, Greece

2 Department of Orthopaedic Surgery, Patras University Hospital, Rion 26500, Greece

3 Department of Radiology, Patras University Hospital, Rion 26500, Greece

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Cases Journal 2009, 2:7365  doi:10.4076/1757-1626-2-7365

Published: 18 August 2009



Intramuscular injections can rarely result in serious infectious complications such as abscesses which may progress to bacteraemia and generalized sepsis. These complications are rare, but can be life threatening, as they can lead to multi-organ failure associated with high morbidity and mortality.

Case presentation

In this report we present two patients who developed life-threatening infections after intramuscular injections. They were admitted to the hospital, had prompt surgical drainage, required ICU admission for severe sepsis, were treated with an early goal-directed therapy protocol and had a good outcome.


Sepsis is a rare, potentially life-threatening complication after intramuscular injections. Timely surgical drainage followed by appropriate ICU care and early goal directed therapy is crucial and may contribute to a good outcome in these rare cases.