Case Report
Sudden elevation of liver enzymes in a 64-year-old patient: a case report
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* Corresponding author: Marcus Wiedmann wiedmann@marienkrankenhaus-berlin.de
1 Department of Internal Medicine II, University of Leipzig, Germany
2 Department of Internal Medicine I, St. Mary's Hospital, Berlin, Germany
3 Office for Internal Medicine and Cardiology, Berlin-Wilmersdorf, Germany
4 Institute of Pathology, Ernst von Bergmann Hospital, Potsdam, Germany
5 Institute of Pathology, St. Gertrauden-Hospital, Berlin, Germany
Cases Journal 2009, 2:205 doi:10.1186/1757-1626-2-205
Published: 18 November 2009Abstract
Eradication of Helicobacter pylori usually consists of a 7-day course of triple therapy including metronidazole or amoxicillin plus clarithromycin plus a proton pump inhibitor. We report about a rare adverse event of Hp eradication in a patient with moderate chronic and moderate active pangastritis. Shortly after the end of treatment cholestatic hepatitis occurred which was most likely related to clarithromycin, perhaps enhanced by amoxicillin. Since liver dysfunction was self-limited, no further treatment was required. In summary, clinicians should be aware about the presented rare adverse event of Helicobacter pylori eradication treatment for a close monitoring of those patients and rapid management of acute liver failure.