A case of polymyositis associated with papillary thyroid cancer: a case report

doi:10.1186/1757-1626-1-289

Cases Journal

Volume 1

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Kalliabakos D
Pappas A
Lagoudianakis E
Papadima A
Chrysikos J
Basagiannis C
Tsakoumagou M
Skanelli Y
Manouras A

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Kalliabakos D
Pappas A
Lagoudianakis E
Papadima A
Chrysikos J
Basagiannis C
Tsakoumagou M
Skanelli Y
Manouras A
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Case Report

A case of polymyositis associated with papillary thyroid cancer: a case report

Dimitrios Kalliabakos¹ , Apostolos Pappas² , Emmanuel Lagoudianakis²^,3 , Artemisia Papadima , John Chrysikos¹ , Christos Basagiannis¹ , Maria Tsakoumagou¹ , Yasemi Skanelli¹ and Andreas Manouras

¹401 General Military Hospital, Mesogeion Avenue 138, 115 25, Athens, Greece

²First Department of Propaedeutic Surgery, Hippocrateion Hospital, Athens Medical School, Q. Sophia 114, 11527, Athens, Greece

³General Surgery, Agamemnonos 17, Alimos, 17456, Athens, Greece

author email corresponding author email

Cases Journal 2008, 1:289doi:10.1186/1757-1626-1-289


Published:	30 October 2008

Abstract

Differentiated thyroid cancer is rarely associated with paraneoplastic events. Polymyositis, an autoimmune inflammatory myopathy, can be manifested as a paraneoplastic syndrome (PS). We report a case of a young woman who developed progressive proximal muscle weakness one and a half year after a total thyroidectomy for papillary thyroid cancer. Clinical features, laboratory results and muscle biopsy led us to the diagnosis of polymyositis, possibly related to her previous malignancy. A search for recurrence of the thyroid carcinoma or other underlying malignancy was fruitless. The patient improved slowly but almost completely after about 6 months of immunosupressive therapy, which she is still receiving.